Meloxicam, a Selective COX-2 Inhibitor, Mediates Hypoxia-Inducible Factor- (HIF-) 1α Signaling in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is regarded as a leading cause of cancer-related deaths, and its progression is associated with hypoxia and the induction of hypoxia-inducible factor (HIF). Meloxicam, a selective cyclooxygenase-2 (COX-2) inhibitor, induces cell death in various malignancies. However,...

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Опубликовано в: :Oxid Med Cell Longev
Главные авторы: Zhou, Yinghong, Dong, Xiaofeng, Xiu, Peng, Wang, Xin, Yang, Jianrong, Li, Lei, Li, Zhongchao, Sun, Pengfei, Shi, Xuetao, Zhong, Jingtao
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128048/
https://ncbi.nlm.nih.gov/pubmed/32273947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7079308
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