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Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches

Metastasis causes most cancer-related deaths, and one poorly understood aspect of metastatic cancer is the adaptability of cells from a primary tumor to create new niches and survive in multiple, different secondary sites. We used quantitative mass spectrometry to analyze the extracellular matrix (E...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Hebert, Jess D., Myers, Samuel A., Naba, Alexandra, Abbruzzese, Genevieve, Lamar, John M., Carr, Steven A., Hynes, Richard O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127975/
https://ncbi.nlm.nih.gov/pubmed/32019869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2961
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