AGO2 mediates MYC mRNA stability in hepatocellular carcinoma

Deregulated RNA binding proteins (RBPs), such as Argonaute 2 (AGO2) mediate tumor-promoting transcriptomic changes during carcinogenesis, including hepatocellular carcinoma (HCC). While AGO2 is well characterized as a member of the RNA-induced silencing complex (RISC), which represses gene expressio...

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Vydáno v:Mol Cancer Res
Hlavní autoři: Zhang, Kai, Pomyen, Yotsawat, Barry, Anna E., Martin, Sean P., Khatib, Subreen, Knight, Lucy, Forgues, Marshonna, Dominguez, Dana A., Parhar, Ravinder, Shah, Ashesh P., Bodzin, Adam S., Wang, Xin Wei, Dang, Hien
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127970/
https://ncbi.nlm.nih.gov/pubmed/31941754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0805
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