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Vimentin coordinates protein turnover at the aggresome during neural stem cell quiescence exit

Maintaining a healthy proteome throughout life is critical for proper somatic stem cell function, yet the complexities of the stem cell response to increases in damaged or aggregated proteins remain unclear. Here we demonstrate that adult neural stem cells (NSCs) utilize aggresomes to recover from d...

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Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Morrow, Christopher S., Porter, Tiaira J., Xu, Nan, Arndt, Zachary P., Ako-Asare, Kayla, Heo, Helen J., Thompson, Elizabeth A.N., Moore, Darcie L.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127969/
https://ncbi.nlm.nih.gov/pubmed/32109376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.01.018
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