Molecular mechanisms of the secretion of cytokines and chemokines from human monocytes activated by pneumococcal surface protein A (PspA): Roles of mitogen-activated protein kinases and NF-kappaB

Pneumococcal surface protein A (PspA) plays a key role in the pathogenesis of invasive pneumococcal infection. PspA might modulate specific immune responses in human population. Circulating monocytes are essential for the innate responses and subsequent acquired immune responses to Streptococcus pne...

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Publicat a:Microb Pathog
Autors principals: Cao, Ju, Chen, Tingmei, Gong, Yi, Ying, Bingwu, Li, Dairong, Xu, Wenchun, Zhang, Xuemei, Wang, Lanlan, Yin, Yibing
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127760/
https://ncbi.nlm.nih.gov/pubmed/20227479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2010.03.001
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