Flaviviral methyltransferase/RNA interaction: Structural basis for enzyme inhibition

Flaviviruses are the causative agents of severe diseases such as Dengue or Yellow fever. The replicative machinery used by the virus is based on few enzymes including a methyltransferase, located in the N-terminal domain of the NS5 protein. Flaviviral methyltransferases are involved in the last two...

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Veröffentlicht in:Antiviral Res
Hauptverfasser: Milani, Mario, Mastrangelo, Eloise, Bollati, Michela, Selisko, Barbara, Decroly, Etienne, Bouvet, Mickaël, Canard, Bruno, Bolognesi, Martino
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127253/
https://ncbi.nlm.nih.gov/pubmed/19501254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2009.03.001
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