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Transition metal-free cross-coupling of furan ring with haloacetylenes

On the example of menthofuran, a naturally abundant compound, it has been shown for the first time that the furan ring can be readily cross-coupled with acylhaloacetylenes in the solid Al(2)O(3) powder at room temperature to afford the corresponding 2-ethynyl derivatives in up to 88% yield. The reac...

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Detalles Bibliográficos
Publicado en:Tetrahedron
Main Authors: Sobenina, Lyubov N., Tomilin, Denis N., Gotsko, Maxim D., Ushakov, Igor A., Trofimov, Boris A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Ltd. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127138/
https://ncbi.nlm.nih.gov/pubmed/32287432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2018.02.024
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