IL-12 deficiency transiently improves viral clearance during the late phase of respiratory tract infection with influenza A virus in mice

T helper 1-driven immune responses have been implicated in protective immunity against viral infections. Interleukin (IL)-12 is a heterodimeric proinflammatory cytokine formed by a p35 and a p40 subunit that can induce differentiation of naïve T cells towards a T helper 1-response. To determine the...

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Publicado en:Antiviral Res
Main Authors: van der Sluijs, Koenraad F., van Elden, Leontine J.R., Xiao, Yanling, Arens, Ramon, Nijhuis, Monique, Schuurman, Rob, Florquin, Sandrine, Jansen, Henk M., Lutter, René, van der Poll, Tom
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier B.V. 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126924/
https://ncbi.nlm.nih.gov/pubmed/16490265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2006.01.007
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