Immunoendocrine dysbalance during uncontrolled T. cruzi infection is associated with the acquisition of a Th-1-like phenotype by Foxp3(+) T cells

We previously showed that Trypanosomacruzi infection in C57BL/6 mice results in a lethal infection linked to unbalanced pro- and anti-inflammatory mediators production. Here, we examined the dynamics of CD4(+)Foxp3(+) regulatory T (Treg) cells within this inflammatory and highly Th1-polarized enviro...

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Publicado en:Brain Behav Immun
Autores principales: González, Florencia B., Villar, Silvina R., Fernández Bussy, Rodrigo, Martin, Gaëlle H., Pérol, Louis, Manarin, Romina, Spinelli, Silvana V., Pilon, Caroline, Cohen, José Laurent, Bottasso, Oscar A., Piaggio, Eliane, Pérez, Ana R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Inc. 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126853/
https://ncbi.nlm.nih.gov/pubmed/25483139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2014.11.016
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