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The activation-dependent induction of APN-(CD13) in T-cells is controlled at different levels of gene expression

Recently, it was shown that aminopeptidase N (E.C. 3.4.11.2, CD13) is up-regulated during mitogenic stimulation of peripheral T-cells. In this study, we demonstrate that the half-life of APN mRNA was considerably prolonged in these cells leading to a 2.7-fold increase of APN transcript level. The ap...

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Détails bibliographiques
Publié dans:FEBS Lett
Auteurs principaux: Wex, Th, Bühling, F, Arndt, M, Frank, K, Ansorge, S, Lendeckel, U
Format: Artigo
Langue:Inglês
Publié: Federation of European Biochemical Societies. Published by Elsevier B.V. 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126794/
https://ncbi.nlm.nih.gov/pubmed/9257688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0014-5793(97)00738-2
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