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EGR1 upregulation following Venezuelan equine encephalitis virus infection is regulated by ERK and PERK pathways contributing to cell death

Venezuelan equine encephalitis virus (VEEV) is a neurotropic virus that causes significant disease in both humans and equines. Here we characterized the impact of VEEV on signaling pathways regulating cell death in human primary astrocytes. VEEV productively infected primary astrocytes and caused an...

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Publicat a:Virology
Autors principals: Dahal, Bibha, Lin, Shih-Chao, Carey, Brian D., Jacobs, Jonathan L., Dinman, Jonathan D., van Hoek, Monique L., Adams, Andre A., Kehn-Hall, Kylene
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126400/
https://ncbi.nlm.nih.gov/pubmed/31733451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2019.10.016
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