New quaternary ammonium camphor derivatives and their antiviral activity, genotoxic effects and cytotoxicity

The synthesis and biological evaluation of a novel series of dimeric camphor derivatives are described. The resulting compounds were studied for their antiviral activity, cyto- and genotoxicity. Compounds 3a and 3d in which the quaternary nitrogen atoms are separated by the C5H10 and С9H18 aliphatic...

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Publicado no:Bioorg Med Chem
Main Authors: Sokolova, Anastasiya S., Yarovaya, Оlga I., Shernyukov, Аndrey V., Pokrovsky, Мichail A., Pokrovsky, Аndrey G., Lavrinenko, Valentina A., Zarubaev, Vladimir V., Tretiak, Tatiana S., Anfimov, Pavel M., Kiselev, Oleg I., Beklemishev, Anatoly B., Salakhutdinov, Nariman F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7126328/
https://ncbi.nlm.nih.gov/pubmed/23993669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.08.014
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