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Pacing a small cage: mutation and RNA viruses

RNA viruses have an extremely high mutation rate, and we argue that the most plausible explanation for this is a trade-off with replication speed. We suggest that research into further increasing this mutation rate artificially as an antiviral treatment requires a theoretical reevaluation, especiall...

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Detalhes bibliográficos
Publicado no:Trends Ecol Evol
Main Authors: Belshaw, Robert, Gardner, Andy, Rambaut, Andrew, Pybus, Oliver G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125972/
https://ncbi.nlm.nih.gov/pubmed/18295930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tree.2007.11.010
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