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Biosynthesis of anti-HCV compounds using thermophilic microorganisms

This work describes the application of thermophilic microorganisms for obtaining 6-halogenated purine nucleosides. Biosynthesis of 6-chloropurine-2′-deoxyriboside and 6-chloropurine riboside was achieved by Geobacillus stearothermophilus CECT 43 with a conversion of 90% and 68%, respectively. Furthe...

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書目詳細資料
發表在:Bioorg Med Chem Lett
Main Authors: Rivero, Cintia W., De Benedetti, Eliana C., Sambeth, Jorge E., Lozano, Mario E., Trelles, Jorge A.
格式: Artigo
語言:Inglês
出版: Elsevier Ltd. 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125738/
https://ncbi.nlm.nih.gov/pubmed/22959520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.08.045
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