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Biosynthesis of anti-HCV compounds using thermophilic microorganisms
This work describes the application of thermophilic microorganisms for obtaining 6-halogenated purine nucleosides. Biosynthesis of 6-chloropurine-2′-deoxyriboside and 6-chloropurine riboside was achieved by Geobacillus stearothermophilus CECT 43 with a conversion of 90% and 68%, respectively. Furthe...
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| 發表在: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier Ltd.
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7125738/ https://ncbi.nlm.nih.gov/pubmed/22959520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.08.045 |
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