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A recombinant Fab neutralizes dengue virus in vitro

A recombinant Fab that recognizes a neutralizing epitope located in the (296–400) region of protein E of dengue virus was obtained from cloned hybridoma cells secreting the mouse monoclonal antibody (mAb) 4E11. The Fd and light chain antibody genes were amplified by polymerase chain reaction, cloned...

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Détails bibliographiques
Publié dans:J Biotechnol
Auteurs principaux: Thullier, P, Lafaye, P, Mégret, F, Deubel, V, Jouan, A, Mazié, J.C
Format: Artigo
Langue:Inglês
Publié: Elsevier Science B.V. 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125516/
https://ncbi.nlm.nih.gov/pubmed/10361725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0168-1656(99)00037-1
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