Artificially decreasing cortical tension generates aneuploidy in mouse oocytes

Human and mouse oocytes’ developmental potential can be predicted by their mechanical properties. Their development into blastocysts requires a specific stiffness window. In this study, we combine live-cell and computational imaging, laser ablation, and biophysical measurements to investigate how de...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Bennabi, Isma, Crozet, Flora, Nikalayevich, Elvira, Chaigne, Agathe, Letort, Gaëlle, Manil-Ségalen, Marion, Campillo, Clément, Cadart, Clotilde, Othmani, Alice, Attia, Rafaele, Genovesio, Auguste, Verlhac, Marie-Hélène, Terret, Marie-Emilie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125192/
https://ncbi.nlm.nih.gov/pubmed/32245998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15470-y
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