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In situ structural characterization of early amyloid aggregates in Alzheimer’s disease transgenic mice and Octodon degus

Amyloid plaques composed of Aβ amyloid peptides and neurofibrillary tangles are a pathological hallmark of Alzheimer’s disease. In situ identification of early-stage amyloid aggregates in Alzheimer’s disease is relevant for their importance as potential targets for effective drugs. Synchrotron-based...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Benseny-Cases, Núria, Álvarez-Marimon, Elena, Aso, Ester, Carmona, Margarita, Klementieva, Oxana, Appelhans, Dietmar, Ferrer, Isidre, Cladera, Josep
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7125182/
https://ncbi.nlm.nih.gov/pubmed/32246090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62708-2
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