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Deubiquitinating Enzymes as Novel Targets for Cancer Therapies
Most ubiquitinated proteins can be recognized and degraded by the 26S proteasome. In the meantime, protein deubiquitination by various deubiquitinating enzymes (DUBs) regulates protein stability within cells, and it can counterbalance intracellular homeostasis mediated by ubiquitination. Numerous re...
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| Publicado no: | Resistance to Proteasome Inhibitors in Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7123001/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-06752-0_15 |
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