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Effect of experimental infection of cattle with bovine herpesvirus-1 (BHV-1) on the ex vivo interaction of bovine leukocytes with Mannheimia (Pasteurella) haemolytica leukotoxin

Mannheimia (Pasteurella) haemolytica A1 produces an extracellular leukotoxin (LKT) that is reported to bind the β(2)-integrin CD11a/CD18 (LEA-1) on ruminant leukocytes. LKT binding induces activation, and subsequent cytolysis, of these cells. It is well known that active viral infection greatly incr...

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Bibliografiske detaljer
Udgivet i:Vet Immunol Immunopathol
Main Authors: Leite, F., Sylte, M.J., O’Brien, S., Schultz, R., Peek, S., van Reeth, K., Czuprynski, C.J.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science B.V. 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119861/
https://ncbi.nlm.nih.gov/pubmed/11825601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0165-2427(01)00397-X
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