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Production of mice from a lethal coronavirus infection in the central nervous system by adoptive transfer of virus-specific T cell clones

The protective effect of a mouse hepatitis virus type-4 (MHV-4)-specific CD8(+) cytotoxic T cell clone and a CD4(+) helper T cell clone was examined by the adoptive transfer into brains of mice lethally infected with MHV-4. Mice survived acute encephalitis if more than 5 × 10(5) cells of either type...

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Detalhes bibliográficos
Publicado no:J Neuroimmunol
Main Authors: Yamaguchi, Kenjiro, Goto, Naoaki, Kyuwa, Shigeru, Hayami, Masanori, Toyoda, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier B.V. 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119813/
https://ncbi.nlm.nih.gov/pubmed/1705943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0165-5728(91)90065-F
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