A novel candidate autoantigen in a multiplex family with multiple sclerosis: prevalence of T-lymphocytes specific for an MBP epitope unique to myelination

Although the major isoform of myelin basic protein (MBP) in the healthy adult CNS is the 18.5-kDa protein, other isoforms containing exon 2 encoded protein (21.5 kDa and 20.2 kDa) exist and are expressed primarily during myelin formation. Since remyelination is a prominent feature in MS lesions, we...

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Veröffentlicht in:J Neuroimmunol
Hauptverfasser: Voskuhl, Rhonda R., McFarlin, Dale E., Tranquill, Laura R., Deibler, Gladys, Stone, Roger, Maloni, Heidi, McFarland, Henry F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Published by Elsevier B.V. 1993
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119790/
https://ncbi.nlm.nih.gov/pubmed/7689584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0165-5728(93)90243-R
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