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Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex antigen expression

We recently found that microglia, brain macrophages, express interleukin-4 (IL-4) receptor mRNA in vitro. Since IL-4 exhibits a variety of functions on the cells of monocyte-macrophage lineage, we examined the effects of IL-4on the functions of microglia. Recombinant IL-4 induced the proliferation o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neuroimmunol
Hauptverfasser: Suzumura, Akio, Sawada, Makoto, Itoh, Yasuhiro, Marunouchi, Tohru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Published by Elsevier B.V. 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119647/
https://ncbi.nlm.nih.gov/pubmed/8071435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0165-5728(94)90031-0
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