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Determination of affinities of a panel of IgGs and Fabs for whole enveloped (influenza A) virions using surface plasmon resonance

The affinity of a panel of neutralizing monoclonal IgGs and their Fab fragments has been measured for the first time with an enveloped type A influenza virus, by surface plasmon resonance (SPR) and the BIAlite(™) instrument. Equilibrium constants could be calculated for four of the five mAbs tested....

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Bibliografiske detaljer
Udgivet i:J Virol Methods
Main Authors: Schofield, D.J., Dimmock, N.J.
Format: Artigo
Sprog:Inglês
Udgivet: Published by Elsevier B.V. 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119561/
https://ncbi.nlm.nih.gov/pubmed/8910646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/0166-0934(96)02086-1
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