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Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition
The secretory pathway in cells possesses an elaborate set of endoproteolytic enzymes that carry out a crucial step in protein precursor maturation. This step is proteolytic activation by cleavage at specific pairs of basic residues. These enzymes, named pro-protein convertases (PCs), are responsible...
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| Veröffentlicht in: | Trends Pharmacol Sci |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier Ltd.
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7119077/ https://ncbi.nlm.nih.gov/pubmed/15925704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2005.04.006 |
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