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ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection

BACKGROUND: Neoantigens can be differentially recognized by T cell receptor (TCR) as these sequences are derived from mutant proteins and are unique to the tumor. The discovery of neoantigens is the first key step for tumor-specific antigen (TSA) based immunotherapy. Based on high-throughput tumor g...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Med Genomics
Hauptverfasser: Li, Yuyu, Wang, Guangzhi, Tan, Xiaoxiu, Ouyang, Jian, Zhang, Menghuan, Song, Xiaofeng, Liu, Qi, Leng, Qibin, Chen, Lanming, Xie, Lu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118832/
https://ncbi.nlm.nih.gov/pubmed/32241270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-0683-4
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