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Innate and Adaptive Immunity through Autophagy

The two main proteolytic machineries of eukaryotic cells, lysosomes and proteasomes, receive substrates by different routes. Polyubiquitination targets proteins for proteasomal degradation, whereas autophagy delivers intracellular material for lysosomal hydrolysis. The importance of autophagy for ce...

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Detalles Bibliográficos
Publicado en:Immunity
Main Authors: Schmid, Dorothee, Münz, Christian
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Inc. 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118777/
https://ncbi.nlm.nih.gov/pubmed/17663981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.07.004
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