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Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens

Cancer drug development has been riddled with high attrition rates, in part, due to poor reproducibility of preclinical models for drug discovery. Poor experimental design and lack of scientific transparency may cause experimental biases that in turn affect data quality, robustness and reproducibili...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Larsson, Peter, Engqvist, Hanna, Biermann, Jana, Werner Rönnerman, Elisabeth, Forssell-Aronsson, Eva, Kovács, Anikó, Karlsson, Per, Helou, Khalil, Parris, Toshima Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118156/
https://ncbi.nlm.nih.gov/pubmed/32242081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62848-5
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