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Chronology of cellular events related to mitochondrial burnout leading to cell death in Fuchs endothelial corneal dystrophy

Fuchs endothelial corneal dystrophy (FECD) is a degenerative eye disease characterized by corneal endothelial cell (CEC) death and the formation of guttae, an abnormal thickening of CEC’s basement membrane. At the tissue level, an oxidative stress causing mitochondrial damage and CEC death have been...

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Publicado en:Sci Rep
Main Authors: Méthot, Sébastien J., Proulx, Stéphanie, Brunette, Isabelle, Rochette, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118119/
https://ncbi.nlm.nih.gov/pubmed/32242036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62602-x
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