Loss of Piccolo Function in Rats Induces Cerebellar Network Dysfunction and Pontocerebellar Hypoplasia Type 3-like Phenotypes

Piccolo, a presynaptic active zone protein, is best known for its role in the regulated assembly and function of vertebrate synapses. Genetic studies suggest a further link to several psychiatric disorders as well as Pontocerebellar Hypoplasia type 3 (PCH3). We have characterized recently generated...

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Pubblicato in:J Neurosci
Autori principali: Falck, Joanne, Bruns, Christine, Hoffmann-Conaway, Sheila, Straub, Isabelle, Plautz, Erik J., Orlando, Marta, Munawar, Humaira, Rivalan, Marion, Winter, York, Izsvák, Zsuzsanna, Schmitz, Dietmar, Hamra, F. Kent, Hallermann, Stefan, Garner, Craig Curtis, Ackermann, Frauke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117892/
https://ncbi.nlm.nih.gov/pubmed/32122952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2316-19.2020
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