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Murine polyomavirus DNA transitions through spatially distinct nuclear replication subdomains during infection

The replication of small DNA viruses requires both host DNA replication and repair factors that are often recruited to subnuclear domains termed viral replication centers (VRCs). Aside from serving as a spatial focus for viral replication, little is known about these dynamic areas in the nucleus. We...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Peters, Douglas K., Garcea, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117779/
https://ncbi.nlm.nih.gov/pubmed/32203554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008403
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