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Interleukin-10 contributes to PGE(2) signalling through upregulation of EP4 via SHIP1 and STAT3

Macrophage cells form part of our first line defense against pathogens. Macrophages become activated by microbial products such as lipopolysaccharide (LPS) to produce inflammatory mediators, such as TNFα and other cytokines, which orchestrate the host defense against the pathogen. Once the pathogen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Samiea, Abrar, Yoon, Jeff S. J., Cheung, Sylvia T., Chamberlain, Thomas C., Mui, Alice L. -F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117666/
https://ncbi.nlm.nih.gov/pubmed/32240179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230427
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