Shulin packages axonemal outer dynein arms for ciliary targeting

The main force generators in eukaryotic cilia and flagella are axonemal outer dynein arms (ODAs). During ciliogenesis, these ~1.8 MDa complexes are assembled in the cytoplasm and targeted to cilia via an unknown mechanism. Here we used the ciliate Tetrahymena to identify two factors (Q22YU3 and Q22M...

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Publicado en:Science
Main Authors: Mali, Girish R., Ali, Ferdos Abid, Lau, Clinton K., Begum, Farida, Boulanger, Jérôme, Howe, Jonathan D., Chen, Zhuo A., Rappsilber, Juri, Skehel, Mark, Carter, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116892/
https://ncbi.nlm.nih.gov/pubmed/33632841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abe0526
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