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Ribosome-associated quality control of membrane proteins at the endoplasmic reticulum

Protein synthesis is an energetically costly, complex and risky process. Aberrant protein biogenesis can result in cellular toxicity and disease, with membrane-embedded proteins being particularly challenging for the cell. In order to protect the cell from consequences of defects in membrane protein...

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Publicat a:J Cell Sci
Autors principals: Phillips, Ben P., Miller, Elizabeth A.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116877/
https://ncbi.nlm.nih.gov/pubmed/33247003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.251983
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