Rapid Structural, Kinetic and Immunochemical Analysis of Alpha-Synuclein Oligomers in Solution

Oligomers comprised of misfolded proteins are implicated as neurotoxins in the pathogenesis of protein misfolding conditions such as Parkinson's and Alzheimer's diseases. Structural, biophysical, and biochemical characterisation of these nanoscale protein assemblies is key to understanding...

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Bibliografiske detaljer
Udgivet i:Nano Lett
Main Authors: Arter, William E., Xu, Catherine K., Castellana-Cruz, Marta, Herling, Therese W., Krainer, Georg, Saar, Kadi L., Kumita, Janet R., Dobson, Christopher M., Knowles, Tuomas P. J.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116857/
https://ncbi.nlm.nih.gov/pubmed/33079553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c03260
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