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A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol
Mitochondrial fidelity is tightly linked to overall cellular homeostasis and is compromised in ageing and various pathologies(1,2,3). Mitochondrial malfunction needs to be relayed to the cytosol, where an integrated stress response is triggered by the phosphorylation of eukaryotic translation initia...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116715/ https://ncbi.nlm.nih.gov/pubmed/32132706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2076-4 |
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