Haptoglobin genotype and outcome after aneurysmal subarachnoid haemorrhage

OBJECTIVE: After aneurysmal subarachnoid haemorrhage (aSAH), extracellular haemoglobin (Hb) in the subarachnoid space is bound by haptoglobin, neutralizing Hb toxicity and helping its clearance. Two exons in the HP gene (encoding haptoglobin) exhibit copy number variation (CNV), giving rise to HP1 a...

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發表在:J Neurol Neurosurg Psychiatry
Main Authors: Morton, Matthew J, Hostettler, Isabel C, Kazmi, Nabila, Alg, Varinder, Bonner, Stephen, Brown, Martin M, Durnford, Andrew, Gaastra, Ben, Garland, Patrick, Grieve, Joan, Kitchen, Neil, Walsh, Daniel, Zolnourian, Ardalan, Houlden, Henry, Gaunt, Tom R, Bulters, Diederik, Werring, David J, Galea, Ian
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116595/
https://ncbi.nlm.nih.gov/pubmed/31937585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2019-321697
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