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Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture

Interactions between RNA-binding proteins (RBPs) and RNAs are critical for cell biology. However, methods to comprehensively and quantitatively assess these interactions within cells were lacking. RNA interactome capture (RIC) employs in vivo UV-crosslinking, oligo(dT) capture and proteomics to iden...

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Détails bibliographiques
Publié dans:Nat Protoc
Auteurs principaux: Perez-Perri, Joel I., Noerenberg, Marko, Kamel, Wael, Lenz, Caroline E., Mohammed, Shabaz, Hentze, Matthias W., Castello, Alfredo
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116560/
https://ncbi.nlm.nih.gov/pubmed/33208978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-020-00404-1
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