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Human Blood CXCR5(+)Foxp3(+) T cells Are Indicators of Ongoing Humoral Activity Not Fully Licensed With Suppressive Function

Germinal center (GC) responses are controlled by T follicular helper (Tfh) and T follicular regulatory (Tfr) cells and are crucial for the generation of high affinity antibodies. Although the biology of human circulating and tissue Tfh cells has been established, the relationship between blood and t...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Fonseca, Valter R, Agua-Doce, Ana, Maceiras, Ana Raquel, Pierson, Wim, Ribeiro, Filipa, Pires, Ana Rita, da Silva, Susana Lopes, Fonseca, João Eurico, Sousa, Ana E, Linterman, Michelle A, Graca, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116402/
https://ncbi.nlm.nih.gov/pubmed/28802258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aan1487
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