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Human CNS barrier-forming organoids with cerebrospinal fluid production
Cerebrospinal fluid (CSF) is a vital liquid, providing nutrients, signalling molecules, and clearing out toxic byproducts from the brain. The CSF is produced by the choroid plexus (ChP), a protective epithelial barrier that also prevents free entry from the blood. Here, we establish human ChP organo...
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| 出版年: | Science |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116154/ https://ncbi.nlm.nih.gov/pubmed/32527923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaz5626 |
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