Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes

RATIONALE: Genome-wide association studies (GWAS) have identified genetic loci associated with insulin resistance (IR) but pinpointing the causal genes of a risk locus has been challenging. OBJECTIVE: To identify candidate causal genes for IR, we screened regional and biologically plausible genes (1...

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Publicat a:Circ Res
Autors principals: Chen, Zhifen, Yu, Haojie, Shi, Xu, Warren, Curtis R., Lotta, Luca A., Friesen, Max, Meissner, Torsten B., Langenberg, Claudia, Wabitsch, Martin, Wareham, Nick, Benson, Mark D., Gerszten, Rob E., Cowan, Chad A.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115834/
https://ncbi.nlm.nih.gov/pubmed/31739742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.315246
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