4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: Synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation

A series of 4-[1-(substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzene sulphonic acids (1-20) was synthesized and evaluated, in vitro, for their antimicrobial activity and the results indicated that compounds 4-[1-(4-Nitrobenzoyl)-1H-benzoimidazol-2-yl]-benzenesulfonic acid (9) and 4-(1-octa...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Yadav, Snehlata, Kumar, Pradeep, De Clercq, Erik, Balzarini, Jan, Pannecouque, Christophe, Dewan, Sharwan Kumar, Narasimhan, Balasubramanian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Masson SAS. 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115694/
https://ncbi.nlm.nih.gov/pubmed/20971531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2010.09.065
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