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Inactivated or damaged? Comparing the effect of inactivation methods on influenza virions to optimize vaccine production
The vast majority of commercially available inactivated influenza vaccines are produced from egg-grown or cell-grown live influenza virus. The first step in the production process is virus inactivation with β-propiolactone (BPL) or formaldehyde (FA). Recommendations for production of inactivated vac...
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| Udgivet i: | Vaccine |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Author(s). Published by Elsevier Ltd.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7115651/ https://ncbi.nlm.nih.gov/pubmed/30765167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.01.086 |
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