SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus

Different forms of SARS coronavirus (SARS-CoV) spike protein-based vaccines for generation of neutralizing antibody response against SARS-CoV were compared using a mouse model. High IgG levels were detected in mice immunized with intraperitoneal (i.p.) recombinant spike polypeptide generated by Esch...

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Bibliografiske detaljer
Udgivet i:Vaccine
Main Authors: Woo, Patrick C.Y., Lau, Susanna K.P., Tsoi, Hoi-wah, Chen, Zhi-wei, Wong, Beatrice H.L., Zhang, Linqi, Chan, Jim K.H., Wong, Lei-po, He, Wei, Ma, Chi, Chan, Kwok-hung, Ho, David D., Yuen, Kwok-yung
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd. 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115571/
https://ncbi.nlm.nih.gov/pubmed/15993989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2005.05.023
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