Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells

The 2′,5′-oligoadenylate synthetase 1 (OAS1) is one of the major interferon-inducible proteins and a critical component of the host defense system against viral infection. A single nucleotide polymorphism (SNP), rs10774671, presumably responsible for alternate splicing of this gene, has frequently b...

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Bibliographic Details
Published in:Hum Immunol
Main Authors: Noguchi, Satoshi, Hamano, Emi, Matsushita, Ikumi, Hijikata, Minako, Ito, Hideyuki, Nagase, Takahide, Keicho, Naoto
Format: Artigo
Language:Inglês
Published: American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115495/
https://ncbi.nlm.nih.gov/pubmed/23220500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2012.11.011
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