Epigenetic activation of FOXF1 confers cancer stem cell properties to cisplatin-resistant non-small cell lung cancer

The underlying molecular mechanisms of cisplatin resistance in non-small cell lung cancer (NSCLC) are unclear. In this study, a novel differential methylation region located in the upstream regulatory region of the forkhead box F1 (FOXF1) gene was identified. The abnormal hypomethylation of FOXF1 in...

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Vydáno v:Int J Oncol
Hlavní autoři: Zhao, Jian, Xue, Xingyang, Fu, Wenfan, Dai, Lu, Jiang, Zeyong, Zhong, Shengpeng, Deng, Boyun, Yin, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115358/
https://ncbi.nlm.nih.gov/pubmed/32319573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2020.5003
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