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Combining in silico and in vitro models to inform cell seeding strategies in tissue engineering

The seeding density of therapeutic cells in engineered tissue impacts both cell survival and vascularization. Excessively high seeded cell densities can result in increased death and thus waste of valuable cells, whereas lower seeded cell densities may not provide sufficient support for the tissue i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J R Soc Interface
Hauptverfasser: Coy, R., Al-Badri, G., Kayal, C., O'Rourke, C., Kingham, P. J., Phillips, J. B., Shipley, R. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115239/
https://ncbi.nlm.nih.gov/pubmed/32208821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0801
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