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Transcriptomic profiling of microglia and astrocytes throughout aging

BACKGROUND: Activation of microglia and astrocytes, a prominent hallmark of both aging and Alzheimer’s disease (AD), has been suggested to contribute to aging and AD progression, but the underlying cellular and molecular mechanisms are largely unknown. METHODS: We performed RNA-seq analyses on micro...

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Pubblicato in:J Neuroinflammation
Autori principali: Pan, Jie, Ma, Nana, Yu, Bo, Zhang, Wei, Wan, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115095/
https://ncbi.nlm.nih.gov/pubmed/32238175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01774-9
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