Development of high-growth influenza H7N9 prepandemic candidate vaccine viruses in suspension MDCK cells

BACKGROUND: Influenza vaccine manufacturers traditionally use egg-derived candidate vaccine viruses (CVVs) to produce high-yield influenza viruses for seasonal or pandemic vaccines; however, these egg-derived CVVs need an adaptation process for the virus to grow in mammalian cells. The low yields of...

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Bibliographic Details
Published in:J Biomed Sci
Main Authors: Tzeng, Tsai-Teng, Chen, Po-Ling, Weng, Tsai-Chuan, Tsai, Shin-Yi, Lai, Chia-Chun, Chou, Hsin-I, Chen, Pin-Wen, Lu, Chia-Chun, Liu, Ming-Tsan, Sung, Wang-Chou, Lee, Min-Shi, Hu, Alan Yung-Chih
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115086/
https://ncbi.nlm.nih.gov/pubmed/32241276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00645-y
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