Characterization of novel monoclonal antibodies against MERS-coronavirus spike protein

Middle East Respiratory Syndrome coronavirus (MERS-CoV) causes severe pulmonary infection, with ∼35 % mortality. Spike glycoprotein (S) of MERS-CoV is a key target for vaccines and therapeutics because S mediates viral entry and membrane-fusion to host cells. Here, four different S subunit proteins,...

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Veröffentlicht in:Virus Res
Hauptverfasser: Goo, Junghyun, Jeong, Yuji, Park, Young-Shin, Yang, Eunji, Jung, Dae-Im, Rho, Semi, Park, Uni, Sung, Hyeyeong, Park, Pil-Gu, Choi, Jung-ah, Seo, Sang Hwan, Cho, Nam Hyuck, Lee, Hyeja, Lee, Jae Myun, Kim, Jae-Ouk, Song, Manki
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Authors. Published by Elsevier B.V. 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114870/
https://ncbi.nlm.nih.gov/pubmed/31945421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2020.197863
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