MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer

BACKGROUND: Epigenetic silencing of retinoic acid (RA) signaling-related genes have been linked with the pathogenesis and clinical outcome in oral squamous cell carcinoma (OSCC) carcinogenesis. However, the precise mechanisms underlying the abnormal silencing of RA signaling-related genes in OSCC ha...

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Publicat a:J Biomed Sci
Autors principals: Shiah, Shine-Gwo, Hsiao, Jenn-Ren, Chang, Hsiao-Ju, Hsu, Yuan-Ming, Wu, Guan-Hsun, Peng, Hsuan-Yu, Chou, Sung-Tau, Kuo, Ching-Chuan, Chang, Jang-Yang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114797/
https://ncbi.nlm.nih.gov/pubmed/32238162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00644-z
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